NABP Exam NAPLEX Topic 10 Question 42 Discussion

Actual exam question for NABP's NAPLEX exam

Question #: 42
Topic #: 10

In the US Nurses' Health Study (NHS) cohort study, where they looked at association of regular aspirin use (two 325 mg tablets/week) and colorectal cancer in 82,911 women found (RR, 0.77; 95% CI, 0.67--0.88) over 20 years of follow-up.

In an another analysis of the NHS, regular aspirin use, investigator also found (hazard ratio [HR]=0.72, 95% CI 0.56--0.92), what does this say about the mortality from colorectal cancer? How can this data best be interpreted?

AThose who takes aspirin 2 times/week have 23% lower risk of colorectal cancer

BThose who takes aspirin 2 times/week have 0.77% lower risk of colorectal cancer

CThose who takes aspirin 2 times/week have 28% lower risk of colorectal cancer

DThose who takes aspirin 2 times/week have 23% reduction in death from colorectal cancer

ENone of the above is correct

Show Suggested Answer

Suggested Answer: A

Relative risk can be stated as 0.77 times as likely or 0.77 times the risk, but it could also be illustrated as a relative risk reduction and stated as a 23% risk reduction or 23% lower risk by taking the medication.

https://www.ncbi.nlm.nih.gov/books/NBK63647/

by Raina at May 09, 2022, 06:07 AM

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