NABP Exam NAPLEX Topic 2 Question 91 Discussion

Actual exam question for NABP's NAPLEX exam

Question #: 91
Topic #: 2

[All NAPLEX Questions]

How does pregabalin work in the treatment of seizures?

ASodium channel blocker

B2 ligand

CAMPA receptor antagonist

DGABA agonist

ESV2A binder

Show Suggested Answer

Suggested Answer: B

Pregabalin works as a ligand of the auxiliary 2 subunit site of certain voltage-dependent calcium channels (VDCCs), and thereby acts as an inhibitor of 2 subunit-containing VDCCs.

by Steffanie at Sep 14, 2024, 10:23 PM

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Cassie

2 months ago

E, SV2A binder, that's the one! It's like pregabalin is the bouncer at the neuron's door, keeping the party under control.

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Thaddeus

2 months ago

GABA agonist, for sure. Pregabalin is like a virtual hug for your neurons, calming them down and preventing seizures.

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Karol

24 days ago

GABA agonist, for sure. Pregabalin is like a virtual hug for your neurons, calming them down and preventing seizures.

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Elroy

25 days ago

E) SV2A binder

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Afton

29 days ago

D) GABA agonist

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Huey

1 months ago

C) AMPA receptor antagonist

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Olga

1 months ago

B) 2 ligand

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Aide

2 months ago

A) Sodium channel blocker

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Chauncey

2 months ago

Hmm, I'm not sure. Maybe we should review the mechanism of action again.

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Corazon

2 months ago

I believe it's actually an SV2A binder.

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Chauncey

2 months ago

I think pregabalin works as a GABA agonist.

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Patti

2 months ago

Hmm, I thought it was an AMPA receptor antagonist. Guess I need to brush up on my pharmacology knowledge.

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Loreta

1 months ago

I guess we all need to review our pharmacology notes.

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Sheridan

1 months ago

I always thought it was an SV2A binder.

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Xochitl

2 months ago

Really? I thought it was a sodium channel blocker.

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Lynelle

2 months ago

I believe it works as a SV2A binder.

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Lelia

2 months ago

Really? I thought it was an AMPA receptor antagonist.

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Rosamond

2 months ago

It's actually a GABA agonist.

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Ligia

2 months ago

It actually works as a GABA agonist.

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Cyndy

3 months ago

I'm pretty sure it's a 2 ligand, so B is the right choice. It binds to a specific receptor that helps regulate neuronal activity.

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Lucy

3 months ago

Pregabalin is a GABA agonist, so D is the correct answer. It enhances the inhibitory effects of GABA in the brain, leading to reduced neuronal excitability and seizure control.

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